March 10, 2011American Journal of Hypertension
Renal Denervation and Hypertension
Why the study?
Does renal denervation reduce blood pressure in patients with uncontrolled essential hypertension?
Population
Patients with uncontrolled essential hypertension
Design
Review
Authors
Discussion
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Member takes
Implication
Should not yet change practice; leaves open confirmation of sustained benefit in randomized trials.
Structured PICO
Does renal denervation reduce blood pressure in patients with uncontrolled essential hypertension?
P
Population
Patients with uncontrolled essential hypertension
I
Intervention
Renal denervation using a novel catheter-based approach with radiofrequency (RF) energy
O
Outcome
Blood pressure reduction and safety profilesurrogate
Renal denervation is a promising catheter-based approach that may provide substantial and sustained blood pressure reduction in patients with uncontrolled essential hypertension.
Limitations
- Limited number of patients in available evidence
- Many open questions remain regarding full potential and possible risks
Cite This Study
Schlaich et al. (2011) studied this question.