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A convenient synthesis of the traditional medicine constituents magnolamide, lobechine and funebral is described. Construction of the 2‐formylpyrrole core of these natural products was achieved by means of a Maillard reaction, involving condensation of the sugar surrogate, dihydropyranone 9, with the requisite primary amines. This approach offers a very direct and general route to the 2‐formylpyrrole ring system.
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Yuen et al. (2014) studied this question.
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