Key result
Antazoline safely and rapidly restored sinus rhythm in 100% of patients who developed sustained atrial fibrillation during ablation of accessory pathways, without completely blocking the pathway.
Why the study?
Does intravenous antazoline restore sinus rhythm in patients with Wolff-Parkinson-White syndrome who develop atrial fibrillation during accessory pathway ablation?
Observational (n=12)
Yes
Does intravenous antazoline restore sinus rhythm in patients with Wolff-Parkinson-White syndrome who develop atrial fibrillation during accessory pathway ablation?
Antazoline safely and rapidly converts atrial fibrillation to sinus rhythm during accessory pathway ablation without completely blocking the pathway, allowing the procedure to continue.
No takes yet. Share an insight, caveat, or question.
May enable uninterrupted accessory pathway ablation by restoring sinus rhythm; hypothesis-generating and requires randomized confirmation before broader adoption.
Piotrowski et al. (2013) conducted an observational in Wolff-Parkinson-White syndrome with sustained atrial fibrillation during ablation (n=12). Antazoline was evaluated on Restoration of sinus rhythm. Antazoline safely and rapidly restored sinus rhythm in 100% of patients who developed sustained atrial fibrillation during ablation of accessory pathways, without completely blocking the pathway.
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