Key result
Volume expansion with 500 mL of normal saline significantly increased cardiac index from 2.46 to 2.64 L/min/m2 (P=0.013) in patients with cardiac tamponade.
Why the study?
Does intravenous volume expansion improve hemodynamic parameters in patients with cardiac tamponade?
Does intravenous volume expansion improve hemodynamic parameters in patients with cardiac tamponade?
Absolute Event Rate: 2.64% vs 2.46%
p-value: p=0.013
Volume expansion improves cardiac output in about half of patients with cardiac tamponade, with baseline systolic blood pressure <100 mm Hg predicting a favorable response.
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Volume expansion may modestly improve hemodynamics in select tamponade patients; leaves open randomized confirmation and outcome effects.
Sagristà-Sauleda et al. (2008) studied Cardiac Tamponade (n=49). Volume expansion (normal saline) vs. Basal state was evaluated on Cardiac index (p=0.013). Volume expansion with 500 mL of normal saline significantly increased cardiac index from 2.46 to 2.64 L/min/m2 (P=0.013) in patients with cardiac tamponade.
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