Why the study?
Does treatment with cyclophosphamide, vincristine, procarbazine, and prednisolone chemotherapy with or without low-dose radiotherapy cause late cardiac dysfunction in childhood Hodgkin's disease survivors?
Does treatment with cyclophosphamide, vincristine, procarbazine, and prednisolone chemotherapy with or without low-dose radiotherapy cause late cardiac dysfunction in childhood Hodgkin's disease survivors?
Childhood Hodgkin's disease survivors treated with chemotherapy and low-dose radiotherapy show minimal late cardiac effects, primarily consisting of subclinical diastolic alterations.
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Subclinical diastolic changes predominate without systolic impairment; leaves open progression risk and surveillance needs in survivors.
Sarıalioğlu et al. (1995) studied this question.
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