Key result
Dense mesh stent implantation combined with release and post-processing techniques achieved a 100% technical success rate with no major adverse events at 30 days in patients with residual aortic dissection.
Why the study?
To preliminarily evaluate the early safety and efficacy of one-stage repair of residual aortic dissection using dense metal mesh stents combined with improved release and post-processing techniques.
Does one-stage repair using dense metal mesh stents improve early safety and efficacy in patients with residual aortic dissection?
Does one-stage repair using dense metal mesh stents improve early safety and efficacy in patients with residual aortic dissection?
One-stage repair of residual aortic dissection using dense mesh stents shows acceptable early safety and efficacy, significantly increasing true lumen volume and promoting false lumen thrombosis.
Early safety appears acceptable for residual aortic dissection; leaves open need for randomized trials before clinical adoption.
ObjectiveThis study aims to preliminarily evaluate the early safety and efficacy of one-stage repair of residual aortic dissection using dense metal mesh stents combined with improved release and post-processing techniques.MethodsA prospective, single-center, single-arm clinical trial was designed and implemented, enrolling patients with residual aortic dissection to undergo metal mesh stent implantation under guidance of stent release and post-processing techniques. Patients received aortic CTA follow-up at 30 days post-surgery to assess early safety and efficacy.ResultsA total of 25 patients were enrolled, 14 in the (sub)acute phase and 11 in the chronic phase. No postoperative deaths, reinterventions, or aortic-related adverse events like malperfusion or ischemia were reported. The immediate technical success rate was 100%. For (sub)acute cases, the true lumen volume increased by 176.10%, while the false lumen decreased by 83.95%. False lumen thrombosis was grade II in two patients (14.29%), grade III in seven (50.00%), and grade IV in five (35.71%). For chronic cases, the true lumen volume increased by 96.92%, while the false lumen decreased by 73.43%. Thrombosis was grade II in three patients (27.27%), grade III in five (45.45%), and grade IV in three (27.27%). Postoperative aortic CTA showed that all visceral artery branches remained patent, and high-risk ischemic branches were converted to non-high-risk.ConclusionsPreliminary results suggest that dense mesh stents combined with release and post-processing techniques have acceptable early safety and efficacy. For acute and chronic residual aortic dissection patients with visceral artery branch involvement, this method may offer an alternative treatment option. Registration no. ChiCTR2200055277.
No takes yet. Share an insight, caveat, or question.
Li et al. (2025) studied Residual aortic dissection (n=25). Dense mesh stent combined with release and post-processing techniques was evaluated on Major adverse events within 30 days post-surgery. Dense mesh stent implantation combined with release and post-processing techniques achieved a 100% technical success rate with no major adverse events at 30 days in patients with residual aortic dissection.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: