Cardiovascular Problems in Pregnant Women With Marfan Syndrome
Key result
A 34-year-old pregnant woman with Marfan syndrome and a 64-mm aortic root aneurysm was successfully managed with beta-blockers, followed by cesarean section at 28 weeks and a Bentall procedure.
Population
1 pregnant 34-year-old Korean woman with Marfan syndrome and severe aortic root aneurysm presenting at 24…
Design
Case_report
Authors
Discussion
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Implication
May inform individualized care in rare high-risk cases; leaves open optimal thresholds and protocols for Marfan aortopathy in pregnancy.
Study Design
Type
Case Report (n=1)
Structured PICO
P
Population
A 34-year-old pregnant woman with Marfan syndrome and a severe aortic root aneurysm who was managed medically until fetal maturity.
I
Intervention
Metoprolol (titrated to 100 mg BID), close inpatient monitoring, cesarean section at 28 weeks' gestation, followed by a Bentall procedure.
O
Outcome
Successful delivery and aortic repair
Demonstrates the successful multidisciplinary management of a pregnant woman with Marfan syndrome and severe aortic root aneurysm using beta-blockers, early cesarean delivery, and subsequent Bentall procedure.
Cite This Study
Goland et al. (2009) conducted a case report in Marfan syndrome with aortic root aneurysm in pregnancy (n=1). Metoprolol, cesarean section, and Bentall procedure was evaluated. A 34-year-old pregnant woman with Marfan syndrome and a 64-mm aortic root aneurysm was successfully managed with beta-blockers, followed by cesarean section at 28 weeks and a Bentall procedure.