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December 26, 2019Journal of Cardiac SurgeryOpen Access

Acute aortic dissection in a patient with Marfan syndrome during advanced pregnancy

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Key result

Urgent cesarean section followed by the Bentall procedure successfully treated a 26-year-old pregnant woman with Marfan syndrome and type A aortic dissection, with both mother and child discharged.

Why the study?

Pregnant patients with Marfan syndrome are at high risk of aortic dissection or rupture during the third trimester and early postpartum period due to pregnancy-related hemodynamic and hormonal changes.

Population

A 26-year-old pregnant woman with MFS in the 30th gestation week presenting with type A aortic dissection

Comparison

Urgent cesarean section followed by the Bentall procedure

Design

Case report

Authors

BKBeti KostadinovskaTokuda HospitalANAleksandar NikolićUniversity of KragujevacDSDimche SlaveskiTokuda Hospital

Discussion

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Implication

Supports multidisciplinary management in rare Marfan-related type A dissection during pregnancy; hypothesis-generating and should not yet change practice.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
A 26-year-old pregnant woman with Marfan syndrome in the 30th gestation week who presented with type A aortic dissection.
I
Intervention
Urgent cesarean section followed by the Bentall procedure
O
Outcome
Maternal and fetal survival and hospital dischargehard clinical

Multidisciplinary management involving urgent cesarean section followed by the Bentall procedure can yield successful maternal and fetal outcomes in pregnant patients with Marfan syndrome presenting with acute type A aortic dissection.

Cite This Study

Kostadinovska et al. (2019) conducted a case report in Marfan syndrome and type A aortic dissection during pregnancy (n=1). Urgent cesarean section followed by the Bentall procedure was evaluated on Clinical outcome (discharge). Urgent cesarean section followed by the Bentall procedure successfully treated a 26-year-old pregnant woman with Marfan syndrome and type A aortic dissection, with both mother and child discharged.

synapsesocial.com/papers/6aa0cc0b500b9604269d2896https://doi.org/10.1111/jocs.14408
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acute Aortic Dissection during Pregnancy2001 · 32 citations
  2. 2DISSECTING ANEURYSM OF THE AORTA IN YOUNG INDIVIDUALS, PARTICULARLY IN ASSOCIATION WITH PREGNANCY. WITH REPORT OF A CASE1944 · 224 citations
  3. 3Gender-Related Differences in Acute Aortic Dissection2004 · 545 citations
  4. 4Acute type A aortic dissection and pregnancy: a population-based study2011 · 103 citations