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Osteoporosis is a progressive metabolic disease characterized by reduced bone mass and disrupted microarchitecture, increasing fracture risk. It primarily affects postmenopausal women, affecting 35.3% of women [ 1 ]. Traditional assessments using bone mineral density (BMD) alone fail to predict fracture risk among individuals with similar values [ 2 ], emphasizing the importance of bone quality, including architectural and compositional characteristics.
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Bedez et al. (2026) studied this question.
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