Causes of Excessive Bleeding in Patients Who Underwent Open-Heart Surgery During the Early Postoperative Period

Objectives: This study aimed to identify the incidence and causes of excessive bleeding during the early postoperative phase of open-heart surgery. Methods: The files of patients who underwent elective open-heart surgery between January 2019 and January 2021 were reviewed. Excessive bleeding was defined according to the amount of hemorrhage during the first 24 h. The patients were divided into the bleeding group (with excessive bleeding, Group B) and control group (no excessive bleeding, Group C). Patients' demographic data, clamping and pumping times, intraoperative interventions, and clinical data, such as the need for blood and blood product replacement in the intensive care unit, were obtained. Measurements were performed using Student's t-test, Mann-Whitney U test, Pearson's chi-squared test, and correlation test. Results: The incidence of bleeding was 9.7%, and the rate of re-exploration was 33%. The presence of chronic obstructive pulmonary disease was significantly higher in Group B (p=0.006). The preoperative use of antiaggregants was significantly higher in Group B than in Group C (p=0.001). No significant difference was observed between the groups in terms of bleeding and coagulation laboratory values as well as the need for intraoperative replacement of blood and blood products. However, the need for postoperative replacement of blood and blood products was significantly higher in Group B (p<0.001). Female sex was found to be negatively correlated with bleeding (p=0.032). Furthermore, a positive correlation was observed between chronic obstructive pulmonary disease, presence of CRF, use of anticoagulant, EuroSCORE, ECD duration, cross-clamping (CC) duration, and bleeding. The incidence of anemia among the patients was 41%.