Key result
Long non-coding RNAs (LncRNAs) act as critical regulators in the development and progression of alcoholic liver disease, offering potential as diagnostic markers and therapeutic targets.
Why the study?
Recent research has highlighted long non-coding RNAs as critical regulators in the development and progression of alcoholic liver disease, but their roles and therapeutic potential required review.
This review highlights the emerging role of long non-coding RNAs as critical regulators, diagnostic markers, and therapeutic targets in alcoholic liver disease.
LncRNAs may inform future ALD biomarker and target research; leaves open clinical translation pending validation trials.
Alcoholic liver disease (ALD) is a spectrum of liver damage caused by chronic alcohol consumption. The disease progresses in stages, starting with simple fatty liver, progressing to alcoholic hepatitis and potentially leading to fibrosis and cirrhosis. The pathophysiology of ALD is complex and involves several cellular and molecular mechanisms. Recent research has highlighted the role of long non-coding RNAs (LncRNAs) as critical regulators in the development and progression of ALD. This article reviews the current understanding of LncRNAs in ALD, focusing on their functions in key pathological processes and their potential as diagnostic markers and therapeutic targets.
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Wang et al. (2024) conducted a review in Alcoholic liver disease (ALD). Long non-coding RNAs (LncRNAs) was evaluated. Long non-coding RNAs (LncRNAs) act as critical regulators in the development and progression of alcoholic liver disease, offering potential as diagnostic markers and therapeutic targets.
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