Key result
Female sex (OR 1.76) and hypertension were significant risk factors for aneurismal subarachnoid hemorrhage, with the highest incidence of ruptures occurring in the spring.
Case-Control (n=244)
No
Odds Ratio: 1.76 (95% CI 1.28–2.42)
In a Chilean population, aneurismal subarachnoid hemorrhage is strongly associated with hypertension and female sex, with a significant seasonal peak in the spring.
May inform risk assessment in hypertensive women; leaves open seasonal mechanisms in this Chilean cohort.
BACKGROUND: Subarachnoid Hemorrhage (SAH) is caused principally by the rupture of intracranial aneurisms. Important risk factors have been described such as age, sex, hypertension (HT) and season of the year, among others. The objective is to investigate the demographic characteristics and possible risk factors in a population of Chilean patients. METHODS: This retrospective study was based on the analysis of 244 clinical records of patients diagnosed with aneurismal SAH who were discharged from the Instituto de Neurocirugía ASENJO in Santiago, Chile. RESULTS: The mean age of patients was 49.85 years and the male:female ratio was 1:2.7. The signs and symptoms were not different between sexes; cephalea (85.7%) was predominant, followed by loss of consciousness, vomiting/nausea and meningeal signs. Risk factors included sex, age and HT. Concordant with other reports, the incidence of SAH was greatest in spring. CONCLUSIONS: The demographic characteristics and risk factors observed in patients with aneurismal SAH treated in ASENJO were comparable to those of other populations. We were not able to conclude that tobacco and alcohol consumption were risk factors for this population.
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Acuña et al. (2011) conducted a case-control in Aneurismal subarachnoid hemorrhage (n=244). Female sex vs. Male sex was evaluated on Aneurismal subarachnoid hemorrhage (OR 1.76, 95% CI 1.28-2.42). Female sex (OR 1.76) and hypertension were significant risk factors for aneurismal subarachnoid hemorrhage, with the highest incidence of ruptures occurring in the spring.
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