Key result
Women had a lower overall risk of non-traumatic subarachnoid hemorrhage compared to men (RR 0.83; 95% CI 0.83-0.84), with the relative risk progressively increasing across older age groups.
Why the study?
The epidemiology of non-traumatic subarachnoid hemorrhage remains unclear, including antecedent characteristics and how sex differences in risk vary with age.
Does the risk of non-traumatic subarachnoid hemorrhage differ between women and men across different age groups?
Population
58.9 million eligible patients aged 18-90y with at least one healthcare visit in the USA
Comparison
Women vs men across age groups
Design
Retrospective cohort study
Authors
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May guide age-stratified SAH risk assessment; leaves open causal mechanisms and generalizability.
Cohort (n=58,900,000)
Yes
Does the risk of non-traumatic subarachnoid hemorrhage differ between women and men across different age groups?
Relative Risk: 0.83 (95% CI 0.83–0.84)
Men have a higher overall risk of non-traumatic subarachnoid hemorrhage driven by younger age groups, while women have a higher risk only after age 75.
Harrison et al. (2023) conducted a cohort in non-traumatic subarachnoid hemorrhage (n=58,900,000). Female sex vs. Male sex was evaluated on first non-traumatic subarachnoid hemorrhage (RR 0.83, 95% CI 0.83-0.84). Women had a lower overall risk of non-traumatic subarachnoid hemorrhage compared to men (RR 0.83; 95% CI 0.83-0.84), with the relative risk progressively increasing across older age groups.
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