September 9, 2013PLoS ONEOpen Access

Risk Factors and Their Combined Effects on the Incidence Rate of Subarachnoid Hemorrhage – A Population-Based Cohort Study

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Population

64,349 Finnish residents participating in the National FINRISK Study between 1972 and 2007. Key exclusion…

Design

Cohort

Follow-up

median 17.9 years

Authors

MKMiikka KorjaUniversity of Helsinki KSKarri SilventoinenUniversity of Helsinki TLTiina LaatikainenPreventive Cardiology

Discussion

Member takes

Implication

May aid SAH risk stratification; extends observational data on CV risks but leaves causal effects open.

Structured PICO

Population

64,349 Finnish residents (mean age 45 years, 51.7% women) participating in the National FINRISK Study between 1972 and 2007. Key exclusion: persons with a non-fatal subarachnoid hemorrhage (SAH) before baseline.

Outcome

First ever fatal or non-fatal subarachnoid hemorrhage (SAH) eventhard clinical

Traditional cardiovascular risk factors, along with previous myocardial infarction and maternal history of premature stroke, strongly and synergistically increase the long-term risk of subarachnoid hemorrhage.

Limitations

The independent effect of increased alcohol use on the SAH risk could not be reliably determined due to confounding by smoking.
The study is based on single baseline pre-morbid data collection, not on longitudinal assessments, which may skew the value of assessed modifiable risk factors.

Cite This Study

Korja et al. (2013) studied this question.

synapsesocial.com/papers/6a809d1003a7c7d587caf833 https://doi.org/10.1371/journal.pone.0073760

Topics

Hypertension management

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Risk Factors and Their Combined Effects on the Incidence Rate of Subarachnoid Hemorrhage – A Population-Based Cohort Study

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Topics

Risk Factors and Their Combined Effects on the Incidence Rate of Subarachnoid Hemorrhage – A Population-Based Cohort Study

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Topics

Also Consider