Risk factors for subarachnoid haemorrhage: a nationwide cohort of 950 000 adults
Why the study?
Subarachnoid haemorrhage has high mortality and disability, but its causes remain poorly understood.
What are the sex-specific risk factors for subarachnoid haemorrhage in adults?
Population
949 683 persons aged 25 to 90 years without prior SAH from 21 cohorts
Comparison
Assessment of risk factors for SAH including smoking, BMI, blood pressure, and education
Design
Nationwide cohort consortium study
Follow-up
13 704 959 person-years
Authors
Discussion
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Member takes
Implication
Smoking associated with higher SAH risk in women than men; extends sex-specific data but should not yet change practice.
Structured PICO
What are the sex-specific risk factors for subarachnoid haemorrhage in adults?
P
Population
949,683 adults aged 25-90 years (330,334 women) with no history of subarachnoid haemorrhage (SAH) at baseline, from 21 population-based cohorts in Sweden.
I
Intervention
Risk factors including smoking, BMI, blood pressure, and education level
O
Outcome
First-ever fatal or non-fatal subarachnoid haemorrhage (SAH)hard clinical
Smoking is a significantly stronger risk factor for subarachnoid haemorrhage in women compared to men, highlighting the need for targeted public health initiatives.
Cite This Study
Sundström et al. (2019) studied this question.