Why the study?
Does oral anticoagulation reduce the risk of systemic thromboembolism in patients with chronic heart failure?
Population
406 consecutive patients with chronic heart failure, mean LVEF 23 +/- 8%, 200 in NYHA functional class III-IV.
Comparison
Oral anticoagulants (n=232) vs No oral anticoagulants (n=174)
Design
Cohort
Follow-up
16 +/- 11 months
Authors
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Low embolism rates in chronic HF did not differ by anticoagulation; leaves open OAC benefit in sinus rhythm while identifying AF as higher-risk subgroup.
Does oral anticoagulation reduce the risk of systemic thromboembolism in patients with chronic heart failure?
In patients with chronic heart failure and sinus rhythm, the incidence of systemic thromboembolism is low regardless of anticoagulant treatment, whereas atrial fibrillation identifies a high-risk subgroup.
Cioffi et al. (1996) studied this question.
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