Key result
Pulse arrival time showed a strong negative correlation with systolic blood pressure across exercise types, but its correlation with diastolic blood pressure varied significantly by exercise modality.
Why the study?
The precise relationship between BP parameters and PAT under varying conditions lacks a complete understanding, and simple test protocols may fail to demonstrate this relationship.
Does pulse arrival time (PAT) accurately track changes in systolic and diastolic blood pressure during different exercise modalities in adults?
Observational (n=75)
No
Does pulse arrival time (PAT) accurately track changes in systolic and diastolic blood pressure during different exercise modalities in adults?
Effect estimate: PAT-SBP r = -0.82; PAT-DBP r = 0.25 (full protocol)
Pulse arrival time correlates strongly with systolic blood pressure but has an inconsistent relationship with diastolic blood pressure across different exercise modalities, challenging its use as a standalone surrogate for comprehensive blood pressure monitoring.
OBJECTIVE: Pulse arrival time (PAT) is a potential main feature in cuff-less blood pressure (BP) monitoring. However, the precise relationship between BP parameters and PAT under varying conditions lacks a complete understanding. We hypothesize that simple test protocols fail to demonstrate the complex relationship between PAT and both SBP and DBP. Therefore, this study aimed to investigate the correlation between PAT and BP during two exercise modalities with differing BP responses using an unobtrusive wearable device. METHODS: Seventy-five subjects, of which 43.7% had a prior diagnosis of hypertension, participated in an isometric and dynamic exercise test also including seated periods of rest prior to, in between and after. PAT was measured using a prototype wearable chest belt with a one-channel electrocardiogram and a photo-plethysmography sensor. Reference BP was measured auscultatory. RESULTS: Mean individual correlation between PAT and SBP was -0.82 ± 0.14 in the full protocol, -0.79 ± 0.27 during isometric exercise and -0.77 ± 0.19 during dynamic exercise. Corresponding correlation between PAT and DBP was 0.25 ± 0.35, -0.74 ± 0.23 and 0.39 ± 0.41. CONCLUSION: The results confirm PAT as a potential main feature to track changes in SBP. The relationship between DBP and PAT varied between exercise modalities, with the sign of the correlation changing from negative to positive between type of exercise modality. Thus, we hypothesize that simple test protocols fail to demonstrate the complex relationship between PAT and BP with emphasis on DBP.
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A 2021 study conducted an observational in Healthy adults and hypertension (n=75). Isometric and dynamic exercise was evaluated on Correlation between pulse arrival time (PAT) and systolic/diastolic blood pressure (PAT-SBP r = -0.82; PAT-DBP r = 0.25 (full protocol)). Pulse arrival time showed a strong negative correlation with systolic blood pressure across exercise types, but its correlation with diastolic blood pressure varied significantly by exercise modality.
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