Key result
The developed RP-HPLC-UV method was successfully employed for the assessment of molnupiravir in bulk powder and pharmaceutical formulation with no significant differences compared to reported methods.
A validated RP-HPLC-UV method can be successfully used for the quality control and assessment of molnupiravir in pharmaceutical formulations.
May support molnupiravir quality control; leaves open broader validation before routine adoption.
, respectively. No significant interference was detected in the presence of the common pharmaceutical formulation excipients. The method was validated following the ICH recommendations. All the obtained results were statistically compared with those using reported methods and there were no significant differences. The method developed in this work was successfully employed for the assessment of MOL in bulk powder and pharmaceutical formulation.
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Annadi et al. (2022) studied this question. RP-HPLC-UV method vs. reported methods was evaluated on Assessment of molnupiravir in bulk powder and pharmaceutical formulation. The developed RP-HPLC-UV method was successfully employed for the assessment of molnupiravir in bulk powder and pharmaceutical formulation with no significant differences compared to reported methods.
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