What question did this study set out to answer?

To biosynthesize iron oxide nanoparticles using Glochidion candolleanum leaf extract and assess their antioxidant, antimicrobial, anticancer, and mosquito larvicidal capabilities.

October 1, 2025ChemistrySelectOpen Access

Biosynthesis of Iron Oxide Nanoparticles Using Glochidion candolleanum Phytochemicals and Their Biomedical Applications

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Authors

MGM GokulDepartment of Biotechnology SMSugumar MohanasundaramSRM Institute of Science and Technology VSVenkatesa Prabhu SundramurthyKarpagam Academy of Higher Education

Discussion

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Overview

In vitro study reveals potent antioxidant, cytotoxic, and larvicidal activities of green-synthesized iron oxide nanoparticles, highlighting their biomedical and vector-control potential.

Key Points

To biosynthesize iron oxide nanoparticles using Glochidion candolleanum leaf extract and assess their antioxidant, antimicrobial, anticancer, and mosquito larvicidal capabilities.
Biosynthesized iron oxide nanoparticles (Fe2O3 NPs) via ethanolic Glochidion candolleanum leaf extract and characterized them using FT-IR, SEM-EDAX, TEM, and XRD.
Evaluated radical scavenging with DPPH, ABTS, and H2O2 assays, antimicrobial activity via zone of inhibition, cytotoxicity against MDA-MB-231 breast cancer cells, and larvicidal activity on Aedes aegypti.
TEM imaging revealed nanoparticle sizes ranging from 13.57 to 27.24 nm, with antioxidant IC50 values of 45.62 µg/mL (DPPH), 56.18 µg/mL (ABTS), and 80.88 µg/mL (H2O2).
Nanoparticles induced zones of inhibition against Escherichia coli (22.05 ± 0.08 mm) and Candida tropicalis (21.15 ± 0.18 mm) at 100 µL/mL, alongside an IC50 of 27.6 µg/mL in MDA-MB-231 breast cancer cells.
Fe2O3 NPs demonstrated lethal toxicity against Aedes aegypti larvae and pupae during vector-control testing.

Cite This Study

Gokul et al. (2025) studied this question.

synapsesocial.com/papers/6a98d2fcd2b4da1de4bd40ee https://doi.org/10.1002/slct.202502814

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October 1, 2025ChemistrySelectOpen Access

Biosynthesis of Iron Oxide Nanoparticles Using Glochidion candolleanum Phytochemicals and Their Biomedical Applications

View Full Paper

Ask AI

Bookmark

Authors

MGM GokulDepartment of Biotechnology SMSugumar MohanasundaramSRM Institute of Science and Technology VSVenkatesa Prabhu SundramurthyKarpagam Academy of Higher Education

Discussion

Member takes

Overview

In vitro study reveals potent antioxidant, cytotoxic, and larvicidal activities of green-synthesized iron oxide nanoparticles, highlighting their biomedical and vector-control potential.

Key Points

To biosynthesize iron oxide nanoparticles using Glochidion candolleanum leaf extract and assess their antioxidant, antimicrobial, anticancer, and mosquito larvicidal capabilities.
Biosynthesized iron oxide nanoparticles (Fe2O3 NPs) via ethanolic Glochidion candolleanum leaf extract and characterized them using FT-IR, SEM-EDAX, TEM, and XRD.
Evaluated radical scavenging with DPPH, ABTS, and H2O2 assays, antimicrobial activity via zone of inhibition, cytotoxicity against MDA-MB-231 breast cancer cells, and larvicidal activity on Aedes aegypti.
TEM imaging revealed nanoparticle sizes ranging from 13.57 to 27.24 nm, with antioxidant IC50 values of 45.62 µg/mL (DPPH), 56.18 µg/mL (ABTS), and 80.88 µg/mL (H2O2).
Nanoparticles induced zones of inhibition against Escherichia coli (22.05 ± 0.08 mm) and Candida tropicalis (21.15 ± 0.18 mm) at 100 µL/mL, alongside an IC50 of 27.6 µg/mL in MDA-MB-231 breast cancer cells.
Fe2O3 NPs demonstrated lethal toxicity against Aedes aegypti larvae and pupae during vector-control testing.

Cite This Study

Gokul et al. (2025) studied this question.

synapsesocial.com/papers/6a98d2fcd2b4da1de4bd40ee https://doi.org/10.1002/slct.202502814

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