Key result
Inherited thrombophilia was detected in 28.6% of infants with peri-neonatal arterial ischemic stroke and was significantly associated with poor neurological outcome (P=0.002).
Population
24 infants affected by peri-neonatal arterial ischemic stroke, divided into acute AIS and presumed…
Design
Cohort
Follow-up
mean 3 years and 1 month (range 1-15 years)
Authors
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May inform prognosis after neonatal stroke; hypothesis-generating and should not yet change practice.
Cohort (n=24)
p-value: p=0.002
Inherited thrombophilia is highly prevalent in presumed peri-neonatal ischemic stroke and serves as a significant prognostic factor for poor long-term neurological outcomes.
Suppiej et al. (2007) conducted a cohort in peri-neonatal arterial ischemic stroke (AIS) (n=24). Inherited thrombophilia vs. Absence of inherited thrombophilia was evaluated on Poor neurological outcome (p=0.002). Inherited thrombophilia was detected in 28.6% of infants with peri-neonatal arterial ischemic stroke and was significantly associated with poor neurological outcome (P=0.002).
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