Key result
Released proplatelets convert into individual platelets via an intermediate preplatelet stage, driven by twisting microtubule-based forces and potentiated by shear.
Authors
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Refines models of platelet biogenesis; extends prior in vitro observations but leaves clinical translation open.
Thon et al. (2010) studied Platelet production. Released proplatelets convert into individual platelets via an intermediate preplatelet stage, driven by twisting microtubule-based forces and potentiated by shear.
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