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September 5, 2007American Journal of Health-System Pharmacy

Targeted pulmonary vasodilators, including epoprostenol, iloprost, and sildenafil, are viable treatment options for pregnant patients with pulmonary arterial hypertension.

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Population

Pregnant women with pulmonary arterial hypertension (PAH)

Design

Review

Key result

Targeted pulmonary vasodilators, including epoprostenol, iloprost, and sildenafil, are viable treatment options for pregnant patients with pulmonary arterial hypertension.

Authors

SHSheilyn HuangEHEvelyn R. Hermes‐DeSantis

Discussion

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Overview

May support targeted vasodilators in pregnant PAH; leaves open need for prospective trials to guide practice.

Structured PICO

P
Population
A review of treatment options for pregnant women with pulmonary arterial hypertension.
I
Intervention
Targeted pulmonary vasodilators (including epoprostenol, iloprost, sildenafil), inhaled nitric oxide, calcium-channel blockers, and low-molecular-weight heparin

Targeted pulmonary vasodilators and low-molecular-weight heparin are viable and necessary treatment options for managing pulmonary arterial hypertension during pregnancy.

Cite This Study

Huang et al. (2007) conducted a review in Pulmonary arterial hypertension in pregnancy. Targeted pulmonary vasodilators (epoprostenol, iloprost, sildenafil) was evaluated. Targeted pulmonary vasodilators, including epoprostenol, iloprost, and sildenafil, are viable treatment options for pregnant patients with pulmonary arterial hypertension.

synapsesocial.com/papers/6a98de3f2d0bc910e975b63fhttps://doi.org/10.2146/ajhp060391
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pulmonary hypertension in pregnancy: treatment with pulmonary vasodilators1999 · 90 citations
  2. 2Management of Eisenmenger Syndrome in Pregnancy With Sildenafil and l-arginine2004 · 100 citations
  3. 3Pregnancy Outcome in Patients With Pulmonary Arterial Hypertension Receiving Prostacyclin Therapy2005 · 107 citations
  4. 4Severe Pulmonary Hypertension during Pregnancy2005 · 347 citations
  5. 5The use of iloprost in early pregnancy in patients with pulmonary arterial hypertension2005 · 103 citations