Diagnosis of Capnocytophaga canimorsus Sepsis by Whole-Genome Next-Generation Sequencing

Maria K. Abril; Adam S. Barnett; Kara Wegermann; Eric Fountain; Andrew D. Strand; Benjamin Heyman; Britton Blough; Aparna Swaminathan; Batu K. Sharma‐Kuinkel; Felicia Ruffin; Barbara D. Alexander; Chad M. McCall; Sylvia F. Costa; Murat O. Arcasoy; David K. Hong; Timothy A. Blauwkamp; Michael A. Kertesz; Vance G. Fowler; Bryan Kraft

doi:10.1093/ofid/ofw144

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Abstract

We report the case of a 60-year-old man with septic shock due to Capnocytophaga canimorsus that was diagnosed in 24 hours by a novel whole-genome next-generation sequencing assay. This technology shows great promise in identifying fastidious pathogens, and, if validated, it has profound implications for infectious disease diagnosis.

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Abril et al. (2016) studied this question.

synapsesocial.com/papers/6a98e04cdea2d226f518e881 https://doi.org/10.1093/ofid/ofw144

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Diagnosis of Capnocytophaga canimorsus Sepsis by Whole-Genome Next-Generation Sequencing

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Diagnosis of Capnocytophaga canimorsus Sepsis by Whole-Genome Next-Generation Sequencing

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