Why the study?
Does a family history of essential hypertension alter blood pressure and heart rate responses to psychological stress and muscle work?
Population
195 relatives of patients from families with essential hypertension in at least two generations, and…
Comparison
Exposure to static and dynamic muscle work and… vs Controls without heredity for hypertension…
Design
Cross-sectional
Authors
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May indicate age-amplified genetic effects on BP regulation in hypertension families; leaves open prospective validation before clinical risk stratification.
Does a family history of essential hypertension alter blood pressure and heart rate responses to psychological stress and muscle work?
Genetic factors associated with essential hypertension may exhibit greater penetrance with increasing age, influencing blood pressure regulation during rest and physiological stress.
Ohlsson et al. (1982) studied this question.
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