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July 1, 1972Cardiovascular Research

Systemic haemodynamics in borderline arterial hypertension: responses to static exercise before and under the influence of propranolol

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Why the study?

Does intravenous propranolol modify the hemodynamic response to static muscular exercise in young patients with borderline arterial hypertension?

Population

Young patients with borderline arterial hypertension and normotensive control subjects

Comparison

Static muscular exercise before and under the… vs Normotensive control subjects; responses before…

Design

Other

Authors

RSR SannerstedtSJS Julius

Discussion

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Overview

Intravenous propranolol does not significantly modify the hemodynamic response to static exercise in young patients with borderline hypertension, suggesting no abnormal acute circulatory regulation or neurogenic hyperreactivity.

Structured PICO

Does intravenous propranolol modify the hemodynamic response to static muscular exercise in young patients with borderline arterial hypertension?

P
Population
Young patients with borderline arterial hypertension and normotensive control subjects
I
Intervention
Static muscular exercise before and under the influence of intravenous propranolol
C
Comparator
Normotensive control subjects; responses before propranolol administration
O
Outcome
Changes in brachial artery blood pressure, heart rate, and cardiac outputsurrogate

Intravenous propranolol does not significantly modify the hemodynamic response to static exercise in young patients with borderline hypertension, suggesting no abnormal acute circulatory regulation or neurogenic hyperreactivity.

Cite This Study

Sannerstedt et al. (1972) studied this question.

synapsesocial.com/papers/6a8b09b4510c7253b5dec6f5https://doi.org/10.1093/cvr/6.4.398
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Role of Parasympathetic Inhibition in the Hyperkinetic Type of Borderline Hypertension1971 · 339 citations
  2. 2Hemodynamic Responses to Tilt and Beta-Adrenergic Blockade in Young Patients with Borderline Hypertension1970 · 65 citations
  3. 3Cardiovascular response to static contraction in borderline hypertension1985 · 7 citations
  4. 4Relationship Between Cardiac Output and Peripheral Resistance in Borderline Hypertension1971 · 171 citations
  5. 5Increased beta-adrenergic tone enhances arterial compliance in hyperkinetic borderline hypertension1989 · 4 citations