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June 1, 1985Clinical CardiologyOpen Access

Cardiovascular response to static contraction in borderline hypertension

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Why the study?

Do young men with borderline hypertension have an exaggerated cardiovascular response to static contraction compared to normotensive controls?

Population

22 young males, comprising 9 with borderline hypertension and 13 normotensive controls.

Comparison

Small and large muscle static contractions. vs Normotensive controls performing the same static…

Design

Cross-sectional, Randomly assigned order for one-arm handgrip and two-leg…

Key result

Static contraction in young men with borderline hypertension resulted in a non-significant 6 mmHg greater increase in mean arterial blood pressure compared to normotensive controls (P>0.1).

Authors

DSDouglas R. SealsPHPeter HansonRWRichard A. Washburn

Discussion

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Overview

Borderline hypertensive young men show normal pressor responses to static exercise; leaves open relevance to older or established hypertension cohorts.

Study Design

Type

RCT (n=22)

Randomization

Randomly assigned order

Structured PICO

Do young men with borderline hypertension have an exaggerated cardiovascular response to static contraction compared to normotensive controls?

P
Population
22 young males (9 with borderline hypertension and 13 normotensive controls) evaluated for cardiovascular responses to 3 minutes of static muscle contractions.
I
Intervention
Small and large muscle static contractions (one-arm handgrip and two-leg extension performed for 3 min at 30% of maximal voluntary contraction).
C
Comparator
Normotensive controls performing the same static contractions.
O
Outcome
Cardiovascular responses including mean intra-arterial blood pressure (MABP), heart rate (HR), and tension.surrogate

Main Result

Mean Difference: 6

p-value: p=>0.1

Young men with borderline hypertension generally show normal cardiovascular regulation during static contraction, though a subset may exhibit hyperreactivity.

Cite This Study

Seals et al. (1985) conducted an RCT in Borderline hypertension (n=22). Static contraction (one-arm handgrip and two-leg extension) vs. Normotensive controls was evaluated on Increase in mean intra-arterial blood pressure (delta MABP) from rest to the end of exercise (MD 6 mmHg, p=>0.1). Static contraction in young men with borderline hypertension resulted in a non-significant 6 mmHg greater increase in mean arterial blood pressure compared to normotensive controls (P>0.1).

synapsesocial.com/papers/6a623d725a5e300a3289e6c8https://doi.org/10.1002/clc.4960080608
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Systemic haemodynamics in borderline arterial hypertension: responses to static exercise before and under the influence of propranolol1972 · 48 citations
  2. 2Hemodynamic Responses to Tilt and Beta-Adrenergic Blockade in Young Patients with Borderline Hypertension1970 · 66 citations
  3. 3Similarity of Cardiovascular Response to Upper and Lower Body Static Contraction in Endurance-Trained and Untrained Males1983 · 5 citations
  4. 4Tilt Test for Investigating a Neural Component in Hypertension1967 · 166 citations
  5. 5Haemodynamic effects of static and dynamic exercise in males with arterial hypertension of varying severity1978 · 24 citations