Key result
Static contraction in young men with borderline hypertension resulted in a non-significant 6 mmHg greater increase in mean arterial blood pressure compared to normotensive controls (P>0.1).
Why the study?
Do young men with borderline hypertension have an exaggerated cardiovascular response to static contraction compared to normotensive controls?
RCT (n=22)
Randomly assigned order
Do young men with borderline hypertension have an exaggerated cardiovascular response to static contraction compared to normotensive controls?
Young men with borderline hypertension generally show normal cardiovascular regulation during static contraction, though a subset may exhibit hyperreactivity.
Borderline hypertensive young men show normal pressor responses to static exercise; leaves open relevance to older or established hypertension cohorts.
Nine young males with borderline hypertension (BH) (mean age +/- SD, 25 +/- 5 yr) and 13 young male normotensive controls (NT) (24 +/- 3 yr) were studied to determine their cardiovascular responses to small and large muscle static contractions. The subjects performed one-arm handgrip and two-leg extension in a randomly assigned order for 3 min at 30% of maximal voluntary contraction. Mean intra-arterial blood pressure (MABP), heart rate (HR), and tension were measured throughout the contractions. Borderline hypertensive patients had a higher MABP at rest (p less than 0.005) and at the end of both types of static contractions (p less than 0.05). The average increases in MABP from rest to the end of exercise (delta MABP) were slightly greater for the BH patients (6 mmHg), but these differences were not significant (p greater than 0.1). However, a greater percentage of BH patients were hyperreactive to handgrip (delta BP greater than 35 mmHg) and leg extension (delta BP greater than 40 mmHg) when compared to controls. These data indicate that, in general, young men with borderline hypertension demonstrate normal cardiovascular regulation in response to static contraction, but that a portion of this population may be hyperreactive to this type of circulatory stress.
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Seals et al. (1985) conducted an RCT in Borderline hypertension (n=22). Static contraction (one-arm handgrip and two-leg extension) vs. Normotensive controls was evaluated on Increase in mean intra-arterial blood pressure (delta MABP) from rest to the end of exercise (MD 6 mmHg, p=>0.1). Static contraction in young men with borderline hypertension resulted in a non-significant 6 mmHg greater increase in mean arterial blood pressure compared to normotensive controls (P>0.1).
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