Key result
Low levels of plasma high-density lipoprotein cholesterol are associated with an increased risk of atherosclerotic cardiovascular disease.
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Design
Review
Reinforces HDL-C as ASCVD risk marker; confirms association but leaves open causality and therapeutic targeting.
Epidemiological, clinical, and experimental studies have shown that low levels of plasma high-density lipoprotein cholesterol (HDL-C) are associated with increased atherosclerotic cardiovascular disease (CVD) [...].
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Julve et al. (2021) studied this question. Low levels of plasma high-density lipoprotein cholesterol are associated with an increased risk of atherosclerotic cardiovascular disease.
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