Key result
Higher HbA1c levels were significantly positively correlated with increased severity of coronary artery disease as measured by the Gensini score (p<0.01).
Why the study?
Diabetes mellitus is a major risk factor for coronary artery disease, motivating an assessment of the relation between glycated hemoglobin levels and CAD severity in diabetic patients.
Cross-Sectional (n=200)
No
HbA1c-CAD severity link in diabetes is hypothesis-generating; prospective studies needed before any risk-stratification role.
Background: Diabetes Mellitus (DM) is known to cause microvascular and possibly macrovascular complications as it one of the major risk factors for Coronary Artery Disease (CAD). CAD is a major cause of death in developed countries. The study aims to assess the relation of glycated Hemoglobin (HbA1c) levels and severity of CAD in diabetic patients.
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Eldin et al. (2020) conducted a cross-sectional in Type 2 diabetes mellitus and coronary artery disease (n=200). Glycated hemoglobin (HbA1c) level vs. Lower HbA1c levels was evaluated on Severity of coronary artery disease measured by Gensini score (p=<0.01). Higher HbA1c levels were significantly positively correlated with increased severity of coronary artery disease as measured by the Gensini score (p<0.01).
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