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A young woman suffering from recurrent erythema multiforme associated with relapsing gluteal herpes simplex is presented, in whom long-term treatment with oral acyclovir prevented herpes episodes as well as erythema multiforme. Erythema multiforme is an acute self-limiting syndrome with distinctive skin lesions with or without mucosal lesions. An association of the syndrome with recurrent herpes simplex virus infection has been known for a long time, although the exact relationship has not been established.
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L Molin (1987) studied this question.
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