Key result
Designing randomized clinical trials in surgery presents significant methodological complexities and is more difficult than commonly perceived.
Key points are not available for this paper at this time.
Requires careful planning and resources for surgical RCTs; challenges the notion that such trials are straightforward to design.
Not as easy as you think
No takes yet. Share an insight, caveat, or question.
Raffaele Lombardi (2014) studied this question. Designing randomized clinical trials in surgery presents significant methodological complexities and is more difficult than commonly perceived.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: