Key result
Atrial fibrillation and coronary artery disease share common risk factors but require different risk-stratification schemes and prevention strategies due to distinct differences in pathogenesis.
Although atrial fibrillation and coronary artery disease share common risk factors and aging processes, they require distinct risk-stratification and prevention strategies due to differences in pathogenesis.
Requires separate risk stratification for AF and CAD in practice; leaves open validation of integrated models in prospective studies.
AF and CAD resemble twins; they have common mechanistic backgrounds and common risk factors based on the underlying aging process, and similar therapeutic strategy to prevent thrombosis. However, there are also distinct differences in the pathogenesis and the mechanisms of acute events. Therefore, different risk-stratification schemes and different strategies for the prevention of events are required.
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Masaharu Akao (2013) conducted a review in Atrial fibrillation and coronary artery disease. Atrial fibrillation and coronary artery disease share common risk factors but require different risk-stratification schemes and prevention strategies due to distinct differences in pathogenesis.
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