Why the study?
Does hemodialysis or hemofiltration affect plasma alpha ANF concentrations in patients with chronic renal failure?
Population
Chronic renal failure patients undergoing hemodialysis or hemofiltration, and 7 healthy control subjects.
Comparison
Hemodialysis or hemofiltration for 3 hours vs Healthy controls and comparison between HD and…
Design
Cohort
Follow-up
3 hours
Authors
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Alpha ANF decline during HD/HF may reflect volume status; hypothesis-generating and requires validation before clinical adoption.
Does hemodialysis or hemofiltration affect plasma alpha ANF concentrations in patients with chronic renal failure?
Plasma alpha ANF concentrations are highly elevated in chronic renal failure and decrease during hemodialysis and hemofiltration, suggesting it may be a useful indicator for extracellular volume status.
Alarabi et al. (1991) studied this question.
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