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June 15, 1957JAMA

One Hundred Seventeen Surgically Treated Cases of Valvular Rheumatic Heart Disease

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Why the study?

Does surgical treatment improve clinical outcomes in patients with valvular rheumatic heart disease?

Population

117 patients with valvular rheumatic heart disease.

Design

Case_series

Follow-up

up to 1 year

Authors

KMK. Alvin MerendinoNational Institutes of Health

Discussion

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Implication

Case series support early surgical feasibility in rheumatic valve disease; hypothesis-generating and should not yet change practice.

Structured PICO

Does surgical treatment improve clinical outcomes in patients with valvular rheumatic heart disease?

P
Population
117 patients with valvular rheumatic heart disease (92 with predominant mitral stenosis, 20 with predominant aortic stenosis).
I
Intervention
Surgical treatment including commissurotomy for mitral stenosis, aortic dilation for aortic stenosis, and open cardiotomy with cardiopulmonary bypass for mitral insufficiency.
O
Outcome
Operative mortality and clinical improvement (change in degree of regurgitation).hard clinical

Early surgical interventions, including commissurotomy and the use of a new oxygenating pump system for cardiopulmonary bypass, demonstrated feasibility and clinical improvement in patients with severe valvular rheumatic heart disease.

Cite This Study

K. Alvin Merendino (1957) studied this question.

synapsesocial.com/papers/6a990ac024d3faa49b74991ahttps://doi.org/10.1001/jama.1957.02980070031007

Topics

Mitral valve interventionValvular heart disease
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Preliminary Evaluation of Transventricular Aortic Commissurotomy with an Improved Dilator1956 · 12 citations
  2. 2Discrepancies between Subjective and Objective Responses to Mitral Commissurotomy1955 · 19 citations
  3. 3THE NUTRITION OF THE HEART THROUGH THE VESSELS OF THEBESIUS AND THE CORONARY VEINS1898 · 198 citations