Why the study?
Does sufentanil compared to fentanyl improve hemodynamic stability, recovery, and respiratory drive in adult patients without cardiac disease undergoing general surgery?
Population
30 adult patients without cardiac disease undergoing general surgical procedures
Comparison
Sufentanil as a supplement to 60% N2O anesthesia vs Fentanyl as a supplement to 60% N2O anesthesia
Follow-up
up to 60 minutes postoperatively
Authors
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May support sufentanil to limit postoperative respiratory depression versus fentanyl; leaves open confirmatory trials in noncardiac surgery.
Does sufentanil compared to fentanyl improve hemodynamic stability, recovery, and respiratory drive in adult patients without cardiac disease undergoing general surgery?
Sufentanil-N2O anesthesia is as effective as fentanyl-N2O in attenuating hemodynamic and hormonal stress responses during general surgery, with potentially less postoperative respiratory depression.
Clark et al. (1987) studied this question.
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