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On histological examination the twelve MSV‐induced tumors in the uterus observed in our study proved to be of fetal origin. Ten of the 12 tumors had the histological and ultrastructural characteristics of a yolk‐sac tumor. The two other tumors examined had a different morphological structure. One was classified as a teratoma with embryonal carcinoma, the other as a carcinosarcoma. In the primary neoplasms virus particles were found. Their ultrastructure was similar to that of MSV. The histology and the electron microscopy results are discussed in relation to the morphogenesis and the occurrence of these tumors in rodents as well as in man.
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Sobis et al. (1973) studied this question.
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