Key result
Patients with stage 2 hypertension had a significantly higher mean left ventricular mass index (107.4 vs 90.9) and left ventricular mass (216.8 vs 164.4) compared to those with stage 1 hypertension.
Why the study?
Does stage 2 hypertension increase left ventricular mass and mass index compared to stage 1 hypertension in adults aged 30 to 60 years?
Cross-Sectional (n=75)
No
Does stage 2 hypertension increase left ventricular mass and mass index compared to stage 1 hypertension in adults aged 30 to 60 years?
Absolute Event Rate: 107.4% vs 90.9%
p-value: p=<0.05
Higher stages of hypertension are associated with increased left ventricular mass and mass index, indicating greater preclinical target organ damage.
LVMI assessment in small hypertensive cohorts may support risk stratification; leaves open clinical adoption pending larger prospective data.
Introduction: Hypertension is one of the leading causes of the global burden of disease and is the most important health problem met by general physicians. The development of left ventricular hypertrophy increases with the severity of hypertension. Hypertension causes increase in left ventricular mass. Left ventricular mass index is a surrogate of left ventricular hypertrophy and a predictor of cardiac morbidity and mortality in adults with hypertension. Method: 75 individuals aged from 30 to 60 years enrolled in the study from RMMCH after getting ethical approval. After a Detailed history and thorough clinical examination blood pressure was recorded and the Participants were divided based on JNC 8 guidelines as stage 1 and 2. 2 - D echocardiography was performed and Left ventricular mass (LVM) was recorded even in patients with normal ECG. Left ventricular mass index (LVMI) was calculated after getting body surface area (BSA). Result: Blood pressure changes show marked variation in Left ventricular mass as well as Left ventricular mass index. Hypertensive stage 2 showed increased prevalence of LVH and marked rise in LVM and LVMI in comparison with stage 1 individuals. Blood pressure has strong positive correlation with left ventricular mass and also with ventricular mass index. Conclusion: There is rise in LVM and LVMI and increased prevalence of preclinical target organ damage when blood pressure increased from stage 1 to stage 2. LVMI is strongly related to BP.
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AB et al. (2022) conducted a cross-sectional in Hypertension (n=75). Stage 2 hypertension vs. Stage 1 hypertension was evaluated on Mean Left Ventricular Mass Index (LVMI) (p=<0.05). Patients with stage 2 hypertension had a significantly higher mean left ventricular mass index (107.4 vs 90.9) and left ventricular mass (216.8 vs 164.4) compared to those with stage 1 hypertension.
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