Key result
Spinal anaesthesia with bupivacaine and low-dose fentanyl (0.25 μg/kg) for caesarean section resulted in low rates of adverse effects, most commonly spinal hypotension (12%) and spinal headache (11%).
Why the study?
Obstetric anaesthetists care for both mother and unborn baby during caesarean sections, prompting an evaluation of the adverse effects of spinal anaesthesia.
What are the adverse effects of spinal anaesthesia with bupivacaine and fentanyl in full-term, low-risk pregnant patients undergoing caesarean section?
Observational (n=100)
No
What are the adverse effects of spinal anaesthesia with bupivacaine and fentanyl in full-term, low-risk pregnant patients undergoing caesarean section?
Spinal anaesthesia with bupivacaine and low-dose fentanyl for caesarean section is associated with a low incidence of adverse effects, most commonly spinal hypotension and headache.
Adverse effects were infrequent with bupivacaine-fentanyl spinal for low-risk caesarean; supports use but leaves open need for randomized confirmation.
Background: Obstetric anaesthetists while providing anaesthesia for caesarean sections, provide care for both the mother and the unborn baby. This study was performed to evaluate the adverse effects of spinal anaesthesia for Caesarean section. Methods: The present study is a prospective observational study carried out on 100 full-term, low risk pregnant patients who had caesarean section under spinal anaesthesia at Varun Arjun medical college, Shahjahanpur, U. P., India from January 2022 to December 2022. Results: In our study, 43 (43%) patients were between 26-30 years, 32 (32%) patients were between 31-35 years, 16 (16%) patients were between 36-40 years. The 62 (62%) patients were primigravida while 38 (38%) patients were multigravida. The 66 (66%) patients were delivered by emergency caesarean section while 34 (34%) were delivered by emergency caesarean section. In our study, adverse anaesthetic effects were less. 12 (12%) patients had spinal hypotension, 11 (11%) patients had spinal headache, 10 (10%) patients had pruritus, 9 (9%) patients had shivering, 5 (5%) patients had nausea and vomiting, 4 (4%) patients had less visceral pain and neonatal Apgar score each, 3 (3%) patients had failed regional anaesthesia, 3 (3%) patients had bradycardia while 2 (2%) patients had high spinal anaesthesia, 10 (10%) patients had visceral pain. Conclusions: In our study, combination of bupivacaine and a low dose of fentanyl (0.25 μg/kg) provided excellent surgical anaesthesia with short-lasting postoperative analgesia. There were very few adverse side effects.
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Rani et al. (2023) conducted an observational in Caesarean section (n=100). Spinal anaesthesia with bupivacaine and fentanyl was evaluated on Spinal hypotension. Spinal anaesthesia with bupivacaine and low-dose fentanyl (0.25 μg/kg) for caesarean section resulted in low rates of adverse effects, most commonly spinal hypotension (12%) and spinal headache (11%).
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