Key result
A 4-year-old girl with recurrent hemorrhagic pericardial effusion was diagnosed with diffuse lymphangiohemangiomatosis and died from progressive respiratory failure despite medical and surgical therapy.
Case Report (n=1)
Diffuse lymphangiohemangiomatosis should be considered in the differential diagnosis of unexplained recurrent hemorrhagic pericardial effusion in children.
May support considering lymphangiohemangiomatosis in unexplained pediatric recurrent hemorrhagic pericardial effusion; leaves open optimal management strategies.
INTRODUCTION: Recurrent hemorrhagic pericardial effusion in children with no identifiable cause is a rare presentation. CASE PRESENTATION: We report the case of a 4-year-old Indian girl who presented with recurrent hemorrhagic pericardial effusion. Diffuse lymphangiomatosis was suspected when associated pulmonary involvement, soft tissue mediastinal mass, and lytic bone lesions were found. Pericardiectomy and lung biopsy confirmed the diagnosis of diffuse lymphangiohemangiomatosis. Partial clinical improvement occurred with thalidomide and low-dose radiotherapy, but our patient died from progressive respiratory failure. CONCLUSION: Diffuse lymphangiohemangiomatosis should be considered in the differential diagnosis of hemorrhagic pericardial effusion of unclear cause.
No takes yet. Share an insight, caveat, or question.
Kothari et al. (2010) conducted a case report in Recurrent hemorrhagic pericardial effusion due to diffuse lymphangiohemangiomatosis (n=1). Thalidomide, octreotide, epsilon-aminocaproic acid, low-dose radiotherapy, and pericardiectomy was evaluated on Clinical improvement and survival. A 4-year-old girl with recurrent hemorrhagic pericardial effusion was diagnosed with diffuse lymphangiohemangiomatosis and died from progressive respiratory failure despite medical and surgical therapy.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: