Key result
Cerebral edema (OR 6.8; 95% CI 4.5-10.4) and extraparenchymal bleeding on day 5 CT scan were significant independent predictors of death or disability at 6 months after acute ischemic stroke.
Why the study?
What is the prognostic value of hemorrhagic transformation and cerebral edema on subacute CT scans in patients with acute ischemic stroke?
Population
554 patients with acute ischemic stroke enrolled in the Multicenter Acute Stroke Trial-Italy study in whom a…
Design
Cohort
Follow-up
6 months
Authors
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Subacute CT features may refine 6-month prognostication after ischemic stroke; extends prior associations but leaves open whether targeted interventions improve outcomes.
Cohort (n=554)
Yes
What is the prognostic value of hemorrhagic transformation and cerebral edema on subacute CT scans in patients with acute ischemic stroke?
Odds Ratio: 6.8 (95% CI 4.5–10.4)
Extraparenchymal bleeding and cerebral edema on subacute CT scans are strong independent predictors of death or disability at 6 months in patients with acute ischemic stroke.
Motto et al. (1999) conducted a cohort in acute ischemic stroke (n=554). Cerebral edema and extraparenchymal bleeding on subacute CT scan vs. Absence of these findings was evaluated on Death or disability at 6 months (unfavorable outcome) (OR 6.8, 95% CI 4.5 to 10.4). Cerebral edema (OR 6.8; 95% CI 4.5-10.4) and extraparenchymal bleeding on day 5 CT scan were significant independent predictors of death or disability at 6 months after acute ischemic stroke.
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