What question did this study set out to answer?

To compare the individual and combined diagnostic accuracy of transthoracic echocardiography, transesophageal echocardiography, and cardiac computed tomography against surgical or autopsy findings in infective endocarditis.

August 25, 2023Journal of Clinical MedicineOpen Access

The Role of Echocardiography and Cardiac Computed Tomography in Diagnosis of Infective Endocarditis

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Authors

APAna PetkovićUniversity of Belgrade NMNemanja MenkovićUniversity Clinical Centre OPOlga PetrovićUniversity of Belgrade

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Implication

Diagnostic cohort study demonstrates superior lesion detection with cardiac computed tomography over echocardiography in infective endocarditis, suggesting added value for combined imaging.

Key Points

To compare the individual and combined diagnostic accuracy of transthoracic echocardiography, transesophageal echocardiography, and cardiac computed tomography against surgical or autopsy findings in infective endocarditis.
Evaluated 78 patients (mean age 52.29 ± 16.62 years; male-to-female ratio 2:1) with definite infective endocarditis who underwent TTE, TEE, and CCT.
Assessed valvular and paravalvular lesions across 85 valves (70 native, 13 prosthetic, 2 Ozaki procedures), 1 central shunt, and 4 pacemaker leads using surgical or autopsy confirmation as the reference standard.
Calculated sensitivity, specificity, diagnostic accuracy, positive predictive value, and negative predictive value for each modality individually and in combination.
For valvular lesions, sensitivity and specificity were 91.6% and 20% for CCT, 65.5% and 57.9% for TTE, and 60% and 84% for TEE; combined imaging achieved 96.6% sensitivity and 0% specificity.
For paravalvular lesions, sensitivity and specificity were 100% and 0% for CCT, 46% and 10.5% for TTE, and 14.7% and 100% for TEE; combined imaging achieved 100% sensitivity and 0% specificity.
Combined use of echocardiography and CCT demonstrated statistically significant diagnostic improvement over single-modality imaging, especially for prosthetic valve involvement and invasive native-valve lesions.

Cite This Study

Petković et al. (2023) studied this question.

synapsesocial.com/papers/6a9928783e4cc22aad7487c6 https://doi.org/10.3390/jcm12175482

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Implication

Diagnostic cohort study demonstrates superior lesion detection with cardiac computed tomography over echocardiography in infective endocarditis, suggesting added value for combined imaging.

The Role of Echocardiography and Cardiac Computed Tomography in Diagnosis of Infective Endocarditis

Discussion

Member takes

Implication

Key Points

Cite This Study

The Role of Echocardiography and Cardiac Computed Tomography in Diagnosis of Infective Endocarditis

Discussion

Member takes

Implication

Key Points

Cite This Study

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