Clinical Staff Conference1 September 1959IDIOPATHIC HYPOALBUMINEMIAS: CLINICAL STAFF CONFERENCE AT THE NATIONAL INSTITUTES OF HEALTHROBERT S. GORDON JR., M.D., FREDERIC C. BARTTER, M.D., THOMAS WALDMANN, M.D.ROBERT S. GORDON JR., M.D.Search for more papers by this author, FREDERIC C. BARTTER, M.D.Search for more papers by this author, THOMAS WALDMANN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-51-3-553 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDr. Robert S. Gordon, Jr.: I should like to begin this discussion on hypoalbuminemia by showing an illustrative case (figure 1).This two year old child was the product of an apparently normal gestation and showed no signs of disease at birth. From the age of eight months to approximately 20 months he had repeated respiratory infections which produced no permanent residua. Beginning at the age of 16 months, and continuing until the present time, he has had generalized edema, which is well illustrated in the figure. Similar to the typical edema of nephrosis, this patient's edema involves the face...Bibliography1. BennholdPetersRoth HHE: Über einen Fall von kompletter Analbuminaemie ohne vesentliche klinische Krankheitszeichen, Verhandl. d. deutsch. Gesellsch. f. inn. Med. 60 Kongr., p. 630, 1954. CrossrefGoogle Scholar2. AlbrightForbesBartterReifensteinBryantCoxDempsey FAPFCECDLDEF: Studies on the fate of intravenously administered human plasma proteins in idiopathic hypoproteinemia and in osteoporosis, Symposia on Nutrition of the Robert Gould Research Foundation, Vol. II, 1950, Charles C Thomas Co., Spring field, Ill., p. 155. Google Scholar3. AlbrightBartterForbes FFCAP: The fate of human serum albumin administered intravenously to a patient with idiopathic hypoalbuminemia and hypoglobulinemia, Tr. A. Am. Physicians 62: 204, 1949. Google Scholar4. SteinfeldGreeneTabernPatonFlick JLFEDLRRAL: Degradation of iodinated human serum albumin prepared by various procedures, J. Lab. and Clin. Med. 51: 756 (May) 1958. MedlineGoogle Scholar5. CitrinSterlingHalsted YKJA: The mechanism of hypoproteinemia associated with giant hypertrophy of the gastric mucosa, New England J. Med. 257: 906, 1957. CrossrefMedlineGoogle Scholar6. Gordon RS: The preparation of radioactive polyvinylpyrrolidone for medical use, J. Polymer Science 31: 191, 1958. CrossrefGoogle Scholar7. Gordon RS: Exudative enteropathy. Abnormal permeability of the gastrointestinal tract demonstrable with labelled polyvinylpyrrolidone, Lancet 1: 325 (Feb. 14) 1959. CrossrefMedlineGoogle Scholar8. LohssKallee FE: Spurennachweis von Albumin durch Analyse von Antigen-Antikörperpraezipitaten, Clin. Chim. Acta 4: 127, 1959. CrossrefMedlineGoogle Scholar9. Editorial, Lancet 1: 351 (Feb. 14) 1959. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication June 15, 1959.This is an edited transcription of a combined clinical staff conference at the Clinical Center, Bethesda, Maryland, by the National Institutes of Health, Public Health Service, Department of Health, Education, and Welfare.Requests for reprints should be addressed to Robert S. Gordon, Jr., M.D., National Heart Institute, Bethesda 14, Maryland. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Influence of FcRn on Albumin-Fused and Targeted DrugsUnraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based TherapeuticsProtein-losing enteropathy in primary lymphoedema: Mesenteric lymphography and gut resectionInfluence of Methodology on the Detection and Diagnosis of Congenital AnalbuminemiaIncreased Cholesteryl Ester Transfer Activity in Plasma From Analbuminemic PatientsMétabolisme de l'albumineBibliographySerum albuminMetabolism and transport of amphipathic molecules in analbuminemic rats and human subjectsAnalbuminemiaCharacterization of hyperlipidemia m two patients with analbuminemiaAnalbuminemia: Report of a Case and Review of the LiteratureOedema in the newbornAnalbuminaemiaAnalbuminämieAnalbuminemia in Relation to Albumin MetabolismHuman serum albumin: twenty-three genetic variants and their population distributionSekundäre HyperlipoproteinämieAlbumin synthesis rates in patients with hypoproteinemiaRecurrent pleural effusion, protein-losing enteropathy, malabsorption, and mosaic warts associated with generalized lymphatic hypoplasiaEnterales Proteinverlustsyndrom bei einem Hund*Serum Albumin[51Cr] Albumin. biochemical and metabolic studiesCrohn's Disease of the Jejunum with Protein-Losing EnteropathyNephrotisches Syndrom einschließlich renal bedingter ÖdemeHautveränderungen bei inneren ErkrankungenSites of iodide entry into and absorption from the gut lumen and their relevance to the resin-[131I]human serum albumin technique for investigation of protein-losing enteropathyProtein-losing enteropathyAN AUTOPSY CASE OF PRIMARY ACQUIRED AGAMMAGLOBULINEMIA †The Transport of Bilirubin in the Circulating Blood and Its Pathogenetic ImportanceFactors Affecting Lipoprotein Metabolism1 1This work was supported by grants from the Public Health Service (HE 08727-01) and from the Chicago and Illinois Heart Associations.2 2Literature published after June 30, 1964, is not included in this survey.INTESTINAL LYMPHANGIECTASIA MECHANISM OF ENTERIC LOSS OF PLASMA-PROTEIN AND FATLow-Fat Diet in Intestinal LymphangiectasiaProtein-Losing EnteropathySystemic Lymphatic Abnormalities Associated with Gastrointestinal Protein Loss Secondary to Intestinal LymphangiectasiaBlutkreislauf und Transportvorg�nge im menschlichen K�rperProtein-losing Enteropathy in Constrictive PericarditisKlinische UntersuchungenGenetikEnteraler Plasmaeiwei�verlust (?Proteindiarrhoe?) beim nephrotischen SyndromReferencesAbnormal Enteric Loss of Plasma Protein in Gastrointestinal DiseasesProtein-Losing EnteropathyEiweißmangelsyndrom bei exsudativer EnteropathiePlasma Proteins and the Gastrointestinal TractCAUSE OF HYPOALBUMINÆMIA IN PATIENTS WITH GASTROINTESTINAL AND CARDIAC DISEASENEONATAL ŒDEMA DUE TO EXUDATIVE ENTEROPATHYPlasma Protein Exudation in the Peritoneal Cavity During LaparotomyThe Reversibility of Whipple's DiseaseIntestinal Absorption — Aspects of Structure, Function and Disease of the Small-Intestine MucosaExudative gastropathy due to giant hypertrophy of gastric mucosaPROTEIN-LOSING GASTROENTEROPATHY IN CONGESTIVE HEART-FAILUREPassage of serum albumin into the stomachPROTEIN-LOSING ENTEROPATHYDer StofftransportDefektdysproteinämienProteins in Serum and Rectal Mucus of Patients with Ulcerative ColitisThe 131 I-Polyvinylpyrrolidone ( 131 I-PVP)Test in Gastrointestinal Protein LossFecal 131 I-Output After Intravenous Injection of 131 I-Labelled Human Serum Albumin in Normo- and Hypoproteinemic SubjectsFl�ssigkeitshaushalt und Volumenregulation bei extremen Serumalbuminmangel (Analbumin�mie)RADIOACTIVE ISOTOPES IN MEDICINE: A REVIEWProtein-Losing Gastroenteropathy 1 September 1959Volume 51, Issue 3Page: 553-576KeywordsBlood plasmaEdemaGranulomasHypoproteinemiaMedical servicesPlasma proteinsPregnancyPrevention, policy, and public healthProteolysisUpper respiratory tract infections ePublished: 1 December 2008 Issue Published: 1 September 1959 PDF downloadLoading ...
No takes yet. Share an insight, caveat, or question.
Gordon et al. (1959) studied this question.