Why the study?
Does heparin or isoprenaline alter ventilation and perfusion patterns in experimental pulmonary embolism?
Population
Experimental pulmonary embolism model
Design
Preclinical
Authors
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Does not support clinical use of heparin or isoprenaline in pulmonary embolism; leaves open perfusion effects in experimental models.
Does heparin or isoprenaline alter ventilation and perfusion patterns in experimental pulmonary embolism?
Ventilation and perfusion scans in experimental pulmonary embolism show that isoprenaline increases blood flow primarily in non-embolised lung areas without significantly affecting ventilation.
JAMESON et al. (1982) studied this question.
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