Autonomic receptors and nitric-oxide involvements in mediating vasorelaxation effect induced by Syzygium polyanthum leaves extract

Figures

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  Figure 1. Concentration-response curve for extracts-induced relaxations in thoracic aorta rings (n = 5) of (a) Wistar-Kyoto and (b) spontaneously hypertensive rats which were precontracted using phenylephrine (1 μM). Relaxation (%): Percent relaxation (mean ± standard error of mean), AESP: Aqueous extract of Syzygium polyanthum leaves, MESP: Methanolic extract of Syzygium polyanthum leaves. *P < 0.001, extract versus vehicle

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  Figure 2. Concentration-response curves for the effect of muscarinic acetylcholine blockage on (a) Aqueous extract of Syzygium polyanthum- and (b) Methanolic extract of Syzygium polyanthum-induced vasorelaxation in isolated thoracic aorta rings of Wistar-Kyoto (n = 5). *P < 0.05, before versus after blockage

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  Figure 3. Concentration-response curves for the effect of α-adrenergic blockage on (a) Aqueous extract of Syzygium polyanthum-and (b) Methanolic extract of Syzygium polyanthum-induced vasorelaxations in isolated thoracic aorta rings of Wistar-Kyoto (n = 5). *P < 0.001, before versus after blockage

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  Figure 4. Concentration-response curves for the effects of β-adrenergic blockage on (a) Aqueous extract of Syzygium polyanthum-and (b) Methanolic extract of Syzygium polyanthum-induced vasorelaxations in isolated thoracic aorta rings of Wistar-Kyoto (n = 5). *P < 0.05, before versus after blockage

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  Figure 5. Concentration-response curves for the effects of endothelial nitric oxide synthase enzymes blockage on (a) Aqueous extract of Syzygium polyanthum- and (b) Methanolic extract of Syzygium polyanthum-induced vasorelaxations in isolated thoracic aorta rings of Wistar-Kyoto (n = 5). *P < 0.001, before versus after blockage