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January 16, 2023Obstetrics and GynecologyOpen Access

Association Between Influenza Vaccination During Pregnancy and Infant Influenza Vaccination

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Authors

FZFangjun ZhouMLMegan C. LindleyJLJames T. Lee

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Overview

Retrospective study finds higher influenza vaccination rates among infants of mothers vaccinated during pregnancy, suggesting maternal immunization promotes infant vaccine uptake.

Key Points

  • To examine the association between receiving an influenza vaccination during pregnancy and subsequent influenza vaccination status in infants during their first eligible season.
  • Retrospective cohort analysis of 34,919 privately insured individuals aged 15–49 years with singleton live births between September 2017 and February 2018 and their infants using 2017–2019 MarketScan data.
  • Multivariate log-binomial regression models assessed maternal vaccination during the 2017–2018 influenza season and infant vaccination during the 2018–2019 influenza season.
  • Of 34,919 pregnant individuals, 14,168 (40.6%) received an influenza vaccination during pregnancy.
  • Infants born to vaccinated mothers had higher at-least-one-dose coverage than those born to unvaccinated mothers (90.0% vs. 66.3%; aRR 1.34, 95% CI 1.33–1.36).
  • Infants born to vaccinated mothers also had higher at-least-two-dose coverage than those born to unvaccinated mothers (75.5% vs. 51.8%; aRR 1.43, 95% CI 1.41–1.46).

Cite This Study

Zhou et al. (2023) studied this question.

synapsesocial.com/papers/6a99310024d3faa49b74a299https://doi.org/10.1097/aog.0000000000005101
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