Association of Stroke and Myocardial Infarction Symptom Knowledge with Cancer Screening Participation Among Patients with Hypertension and Diabetes: A Cross-Sectional Study in Korea

Q: What are the key findings of this study?

Knowledge of stroke symptoms was significantly associated with higher odds of participating in cancer screening among adults with hypertension (OR 1.250) and diabetes (OR 1.226).

Q: What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Hypertension and Diabetes (n=114083). Intervention: Knowledge of stroke and myocardial infarction symptoms vs. Lack of knowledge of stroke and myocardial infarction symptoms. Primary outcome: Participation in cancer screening within the past 2 years (OR 1.250, 95% CI 1.171-1.335, p=<0.001).

Q: What does this research mean for the field?

Knowledge of stroke and myocardial infarction symptoms is significantly associated with higher participation rates in cancer screening among adults with hypertension and diabetes. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Q: What question did this study set out to answer?

To examine the association between knowledge of stroke and myocardial infarction symptoms and participation in cancer screening among adults with hypertension and diabetes.

Min-Soo Kim; Mina Suh; Hye-Sun Lee; Hye-Sun Lee; Jae Kwan Jun; Hyeon Ji Lee; Hyeon Ji Lee

doi:10.3390/healthcare14172782

September 1, 2026HealthcareOpen Access

Association of Stroke and Myocardial Infarction Symptom Knowledge with Cancer Screening Participation Among Patients with Hypertension and Diabetes: A Cross-Sectional Study in Korea

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Key result

Stroke symptom awareness is linked to ~25% higher odds of cancer screening in hypertensive adults.

OR 1.250
95% CI 1.171-1.335
P<0.001
n=114,083

Figures

Why the study?

The association between knowledge of stroke and myocardial infarction symptoms and cancer screening participation among patients with hypertension or diabetes remains poorly understood.

Does knowledge of stroke and myocardial infarction symptoms improve cancer screening participation in adults with hypertension and diabetes?

Key Points

To examine the association between knowledge of stroke and myocardial infarction symptoms and participation in cancer screening among adults with hypertension and diabetes.
Analyzed cross-sectional data from the 2023 Community Health Survey in Korea, including 45,949 adults with hypertension and 20,357 with diabetes aged ≥40 years.
Used multivariate logistic regression models to assess the relationship between symptom knowledge and cancer screening, followed by age and sex subgroup analyses.
Among patients with hypertension, stroke knowledge (OR: 1.250; 95% CI: 1.171–1.335; p < 0.001) and myocardial infarction knowledge (OR: 1.105; 95% CI: 1.036–1.178; p = 0.002) were significantly associated with cancer screening participation.
Among patients with diabetes, knowledge of stroke (OR: 1.226; 95% CI: 1.121–1.341; p < 0.001) and myocardial infarction symptoms (OR: 1.125; 95% CI: 1.030–1.228; p = 0.009) also showed significant positive associations with cancer screening.
A significant interaction was identified between stroke knowledge and age in hypertension (p for interaction = 0.001), with a stronger association in individuals aged 40–59 years (OR: 1.499; 95% CI: 1.321–1.701; p < 0.001) than those aged ≥60 years (OR: 1.162; 95% CI: 1.084–1.245; p < 0.001).

Study Design

Type

Cross-Sectional (n=114,083)

Structured PICO

Does knowledge of stroke and myocardial infarction symptoms improve cancer screening participation in adults with hypertension and diabetes?

P

Population

114,083 adults aged 40 years and older, including 52,998 with hypertension or diabetes, participating in a nationwide cross-sectional survey in South Korea.

E

Exposure

Comprehensive knowledge of stroke and myocardial infarction (MI) symptoms (classified as 'aware' if scoring 5 out of 5 on symptom recognition).

C

Comparator

Lack of comprehensive knowledge of stroke and MI symptoms (classified as 'unaware' if scoring 0-4).

O

Outcome

Participation in cancer screening in the past 2 years (self-reported).patient reported

Main Result

Odds Ratio: 1.25 (95% CI 1.171–1.335)

p-value: p=<0.001

Knowledge of stroke and MI symptoms is significantly associated with higher participation in cancer screening among adults with hypertension and diabetes, suggesting cardiovascular symptom awareness may serve as a proxy for broader preventive health engagement.

Limitations

Cross-sectional design precludes causal inferences and is subject to reverse causality.
Self-reported survey data is subject to recall and social desirability bias.
Aggregation of all types of cancer screening into a binary outcome lacks stratification by specific screening type.
Potential for residual bias due to unmeasured confounders such as family history or physician recommendation.
Exclusion of participants due to missing covariate data introduced potential attrition bias.
Cross-sectional design precluding causal inferences and subject to reverse causality
Aggregation of all types of cancer screening into a binary outcome without stratification by specific screening type
Potential residual bias due to unmeasured confounders such as family history, physician recommendations, and validated health literacy measures
Lack of information on annual frequency of outpatient visits
Exclusion of approximately 34.6% of the initial sample due to missing covariate data introducing potential attrition bias

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

May support targeted health literacy efforts in cardiometabolic care; leaves open whether symptom knowledge causally boosts screening uptake.

Abstract

Background/Objectives: Patients with hypertension or diabetes often share common risk factors for both cardiovascular diseases and cancer. Although health knowledge is associated with preventive health behaviors, the association between knowledge of stroke and myocardial infarction (MI) symptoms and cancer screening participation remains poorly understood. Methods: This cross-sectional study analyzed data from the 2023 Community Health Survey, including 45,949 adults with hypertension and 20,357 with diabetes aged ≥40 years. Multivariate logistic regression was used to examine the association between knowledge of stroke and MI symptoms and cancer screening participation. Subgroup analyses were conducted according to age and sex. Results: Among patients with hypertension, knowledge of stroke and MI symptoms was significantly associated with higher odds of undergoing cancer screening. Similar associations were observed among patients with diabetes for stroke and MI symptom knowledge. Subgroup analysis revealed that the association for stroke knowledge was significantly more pronounced among adults aged 40–59 years with hypertension, while remaining age and sex subgroup variations were exploratory. Conclusions: Knowledge of stroke and MI symptoms was associated with participation in cancer screening among adults with hypertension and diabetes. These findings suggest that knowledge of cardiovascular symptoms may reflect overall engagement in preventive health behaviors, including cancer screening.

Discussion

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Cite This Study

Kim et al. (2026) conducted a cross-sectional in Hypertension and Diabetes (n=114,083). Knowledge of stroke and myocardial infarction symptoms vs. Lack of knowledge of stroke and myocardial infarction symptoms was evaluated on Participation in cancer screening within the past 2 years (OR 1.250, 95% CI 1.171-1.335, p=<0.001). Knowledge of stroke symptoms was significantly associated with higher odds of participating in cancer screening among adults with hypertension (OR 1.250) and diabetes (OR 1.226).

synapsesocial.com/papers/6a99353a636c6408cfa7d578 https://doi.org/10.3390/healthcare14172782

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Association of Stroke and Myocardial Infarction Symptom Knowledge with Cancer Screening Participation Among Patients with Hypertension and Diabetes: A Cross-Sectional Study in Korea

Figures

Key Points

Study Design

Structured PICO

Main Result

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Association of Stroke and Myocardial Infarction Symptom Knowledge with Cancer Screening Participation Among Patients with Hypertension and Diabetes: A Cross-Sectional Study in Korea

Figures

Key Points

Study Design

Structured PICO

Main Result

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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