Key result
Positive myocardial perfusion studies in ESRD transplant candidates were associated with a significantly increased risk of cardiac death (RR 2.92; 95% CI 1.66-5.12) and myocardial infarction.
Why the study?
Do positive myocardial perfusion studies predict future myocardial infarction and cardiac death in patients with end-stage renal disease assessed for kidney or kidney-pancreas transplantation?
Population
Patients with end-stage renal disease assessed for kidney or kidney-pancreas transplantation from 12 studies.
Comparison
Positive myocardial perfusion studies, including… vs Negative myocardial perfusion studies
Design
Meta-analysis
Authors
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Validates myocardial perfusion imaging for pre-transplant risk stratification in end-stage renal.
Meta-Analysis
Do positive myocardial perfusion studies predict future myocardial infarction and cardiac death in patients with end-stage renal disease assessed for kidney or kidney-pancreas transplantation?
Relative Risk: 2.92 (95% CI 1.66–5.12)
p-value: p=<0.001
Positive myocardial perfusion studies are useful for identifying ESRD patients at significantly increased risk of future myocardial infarction and cardiac death when assessed for kidney or kidney-pancreas transplantation.
Rabbat et al. (2003) conducted a meta-analysis in End-stage renal disease assessed for kidney or kidney-pancreas transplantation. Positive myocardial perfusion studies vs. Negative myocardial perfusion studies was evaluated on Cardiac death (RR 2.92, 95% CI 1.66-5.12, p=<0.001). Positive myocardial perfusion studies in ESRD transplant candidates were associated with a significantly increased risk of cardiac death (RR 2.92; 95% CI 1.66-5.12) and myocardial infarction.
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