Key result
Dobutamine stress echocardiography (pooled sensitivity 0.79, specificity 0.89) had improved accuracy over myocardial perfusion scintigraphy (P=0.02) for detecting CAD in kidney transplant candidates.
Why the study?
What is the diagnostic accuracy of non-invasive cardiac screening tests compared to coronary angiography for detecting coronary artery disease in potential kidney transplant recipients?
Population
Patients considered as potential candidates for kidney transplantation or kidney-pancreas transplantation
Comparison
Non-invasive cardiac screening tests vs Coronary angiography (reference standard)
Design
Meta-analysis
Authors
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Supports preferring dobutamine stress echocardiography for CAD screening in kidney transplant candidates; strengthens meta-analytic guidance for noninvasive test selection.
Meta-Analysis
What is the diagnostic accuracy of non-invasive cardiac screening tests compared to coronary angiography for detecting coronary artery disease in potential kidney transplant recipients?
p-value: p=0.02
Dobutamine stress echocardiography demonstrates moderate sensitivity and specificity for detecting coronary artery disease in kidney transplant candidates, potentially performing better than myocardial perfusion scintigraphy.
Wang et al. (2011) conducted a meta-analysis in Potential kidney transplant recipients with chronic kidney disease. Non-invasive cardiac screening tests (Dobutamine stress echocardiography and myocardial perfusion scintigraphy) vs. Coronary angiography was evaluated on Diagnostic accuracy (sensitivity and specificity) for detecting coronary artery disease (p=0.02). Dobutamine stress echocardiography (pooled sensitivity 0.79, specificity 0.89) had improved accuracy over myocardial perfusion scintigraphy (P=0.02) for detecting CAD in kidney transplant candidates.
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