Why the study?
How does altered preload during the first day of life affect the Doppler flow pattern of right ventricular inflow in normal neonates?
Population
16 normal term neonates, mean birth weight 3,093±381 gm, mean gestational age 39±1 weeks. Mothers had…
Design
Cohort
Follow-up
24 hours
Authors
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Supports preload-dependent neonatal RV filling patterns; hypothesis-generating for Doppler use in transitional circulation.
How does altered preload during the first day of life affect the Doppler flow pattern of right ventricular inflow in normal neonates?
Right ventricular early and late diastolic filling patterns in neonates are dependent on preload increases, likely due to the cessation of left-to-right shunting through the ductus arteriosus.
Harada et al. (1994) studied this question.