Key result
250 kV X-ray therapy for breast carcinoma resulted in pathological ECG changes in 16% of patients, which were symptomless, transient, and mainly occurred in those with prior ischemic heart disease.
Why the study?
Does 250 kV X-ray therapy cause electrocardiographic changes in female patients with breast carcinoma?
Population
25 consecutive female patients with breast carcinoma
Design
Cohort
Follow-up
up to two years
Authors
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May warrant ECG monitoring in breast cancer patients with prior IHD receiving radiotherapy; leaves open relevance of modern techniques.
Cohort (n=25)
Does 250 kV X-ray therapy cause electrocardiographic changes in female patients with breast carcinoma?
Radiotherapy for breast carcinoma can cause transient, symptomless ECG changes, particularly in patients with prior ischemic heart disease, but this should not limit essential treatment.
Jones et al. (1960) conducted a cohort in Breast carcinoma (n=25). 250 kV X-ray therapy was evaluated on Pathological changes in the E.C.G.. 250 kV X-ray therapy for breast carcinoma resulted in pathological ECG changes in 16% of patients, which were symptomless, transient, and mainly occurred in those with prior ischemic heart disease.
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