Key result
Large doses of radiation delivered to the heart during radiotherapy are associated with electrocardiographic changes, arrhythmias, and mediastinopericardial reactions.
Design
Review
Authors
Loading...
Supports cardiac monitoring in thoracic radiotherapy; leaves open modern dose-response quantification.
This historical review highlights early recognition that intensive radiation therapy to the thorax can cause cardiac disturbances, challenging the previous dogma of cardiac immunity to radiation.
Vaeth et al. (1961) conducted a review in Radiation-induced cardiac effects. Ionizing radiation was evaluated. Large doses of radiation delivered to the heart during radiotherapy are associated with electrocardiographic changes, arrhythmias, and mediastinopericardial reactions.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: